170135_inorganicventures_flipping

16.16 ICP-MS Measurement

Quan%ta%ve Analysis Measurement Techniques - External Calibra-on using Calibra-on Standards

• Know or learn about the sample composi-on. A semi-quan-ta-ve analysis using a scanning approach for the en-re mass range allows the analyst to predict interferences and select internal standards and analyte isotopic masses. • Perform interference check analysis. Prepare for the varia-ons in the matrix and analyte composi-on and determine if correc-ons that have been built into the procedure are capable of providing the required accuracy. • Use internal standards to help correct for driD

16.17 ICP-MS Measurement

Quan%ta%ve Analysis Measurement Techniques - External Calibra-on using Internal Standards

• Avoid M interferences • Avoid MO and other molecular interferences • Any naturally occurring internal standard element in your sample must be insignificant in comparison to the amount added • Use internal standard elements as close as possible to the masses of the analyte elements • Make sure the matrix doesn't react with the internal standard to alter (lower) it's concentra-on • Common internal standard elements are 6Li, Be, Sc, Ga, Ge, Y, Rh, In, Cs, Pr, Tb, Ho, Re, Bi, and Th - note many are monoisotopic. • Use peak hopping rather than scanning for the final analysis.