170135_inorganicventures_flipping

Strategies for “tough” Samples

Internal Standards

• Matrix matching (dilution factor) • Instrument drift • Standard bracketing • Calibration curve

Managing interferences • Identification • Correction equations

Strategies for “tough” Samples

Internal Standards • Choosing good IS

• not in sample • similar mass • similar eV • free of interferences (if possible) • Application • let software do it? • manually offline? • when is IS correction ‘too much’?